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Immune response in patients infected with Mycobacterium tuberculosis in Baghdad city, Iraq

Qassim Alfaham, Ahmed Abduljabbar Jaloob Aljanaby

Abstract


Mycobacterium tuberculosis (M. tuberculosis) is one of the most dangerous gram-positive bacteria cause many deaths in every year worldwide especially in developing countries. A total number of 53 patients infected M. tuberculosis and 30 healthy individuals were included in this study. Serum concentration of CD56 and CD19 were measurement by ELISA. The results showed that there was significant increase in serum concentration of CD56 and CD19 in patients infected with MDR M. tuberculosis as compared with patients infected with non-MDR M. tuberculosis and healthy individuals. These results suggested that B-cell (CD56) and natural killer cell (CD19) play an important role in patients with M. tuberculosis duo to amplified and regulate the humoral immunity by positive synergism effect between B-cell natural killer cell.


Keywords


Mycobacterium tuberculosis, Immune response, CD56, CD19, Multi-drug resistance.

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References


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